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The Hershey and Chase Experiments

In 1952 (7 years after Avery's demonstration that genes were DNA), two geneticists:

provided further proof. They worked with a DNA virus, called T2, which infects E. coli (and so is a bacteriophage).

The figure shows the essential elements of the infective cycle of DNA bacteriophages like T2.

Bacteriophages produced within bacteria growing in radioactive culture medium will themselves be radioactive.

Hershey and Chase found that

From these experiments, it was clear that

So here is further proof that genes are DNA.

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19 April 2014